Description
HYDROCODONE (10 MG) AND ACETAMINOPHEN (325 MG) [IMPRINT M367] (20 TABLETS PACK) – NATCO
Product Overview
Hydrocodone 10 mg and Acetaminophen 325 mg [Imprint M367] is a prescription combination pain relief medication manufactured by NATCO. Each tablet contains 10 milligrams of hydrocodone bitartrate, an opioid analgesic, and 325 milligrams of acetaminophen (paracetamol), a non-opioid pain reliever. This formulation provides effective management of moderate to moderately severe pain when alternative treatments are insufficient.
The imprint “M367” identifies the white, oblong tablet as Hydrocodone/Acetaminophen 10/325 mg, ensuring authenticity and pharmaceutical precision. NATCO’s formulation meets strict quality and safety standards, offering reliable pain management for patients who require opioid-based therapy under medical supervision.
Key Features
- Manufacturer: NATCO
- Active Ingredients: Hydrocodone bitartrate (10 mg) and Acetaminophen (325 mg)
- Tablet Imprint: M367
- Tablet Color & Shape: White, capsule-shaped tablet
- Pack Size: 20 tablets per pack
- Usage: Oral administration only
- Schedule: Prescription-only controlled substance (C-II in the U.S.)
Mechanism of Action
- Hydrocodone acts on the central nervous system (CNS) to block pain signals and alter the body’s perception of pain.
- Acetaminophen enhances hydrocodone’s analgesic effects and also reduces fever by acting on the hypothalamic heat-regulating center.
Together, they provide synergistic pain relief, making the medication suitable for short-term management of pain following injury, surgery, or chronic conditions requiring controlled analgesia.
Indications
This medication is commonly prescribed for:
- Moderate to severe acute pain
- Post-operative pain management
- Chronic pain not adequately controlled by non-opioid analgesics
Dosage and Administration
The typical adult dosage is 1 tablet every 4 to 6 hours as needed for pain, not exceeding 6 tablets in 24 hours, depending on the patient’s condition and medical supervision. Dosage should always be individualized and adjusted for tolerance, response, and the patient’s overall health status.
⚠️ Important: Never exceed the recommended acetaminophen limit (4,000 mg per day) to prevent liver toxicity.
Possible Side Effects
Common side effects may include:
- Drowsiness or dizziness
- Nausea or vomiting
- Constipation
- Lightheadedness
Serious side effects may include respiratory depression, allergic reactions, or liver damage (with acetaminophen overdose). Seek immediate medical attention if severe symptoms occur.
Warnings and Precautions
- Addiction, Abuse, and Misuse: Hydrocodone is habit-forming; use only as directed by a licensed healthcare professional.
- Liver Toxicity: Acetaminophen overdose can cause serious liver injury. Avoid concurrent use of other acetaminophen-containing products.
- Interactions: Avoid alcohol, sedatives, and other CNS depressants.
- Pregnancy: Use only if the potential benefit justifies the potential risk to the fetus.
Storage Instructions
Store at room temperature (20°C to 25°C / 68°F to 77°F), away from moisture, heat, and direct light. Keep out of reach of children and never share with others.
Why Choose NATCO’s Hydrocodone/Acetaminophen (M367)
- Pharmaceutical-grade formulation ensuring consistent potency and purity
- Trusted manufacturer adhering to international quality standards
- Fast-acting and long-lasting pain control
- Compact 20-tablet pack, ideal for short-term pain therapy

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